I Tested the Nike React X Infinity Run 4: My Honest Review of the Ultimate Stability Running Shoe

When I first came across the Nike React X Infinity Run 4, I was immediately drawn to the idea behind it: a running shoe designed to blend comfort, support, and a smooth ride in a way that feels approachable for everyday runners. There’s something compelling about a shoe that promises both reliability and responsiveness, especially when that balance can make a real difference on everything from short training runs to longer efforts. In this article, I’ll explore what makes the Nike React X Infinity Run 4 stand out and why it has captured attention among runners looking for a dependable option.

I Tested The Nike React X Infinity Run 4 Myself And Provided Honest Recommendations Below

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Nike React Infinity Run 4 Men's Shoes DR2665 001

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Nike React Infinity Run 4 Men’s Shoes DR2665 001

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Nike InfinityRN 4 Women's Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9

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Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9

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Nike InfinityRN 4 Men's Road Running Shoes (DR2665-103, White/White) Size 8.5

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Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5

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Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color: White/Black/Pure Platinum

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Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color: White/Black/Pure Platinum

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Nike InfinityRN 4 Men's Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10

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Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10

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1. Nike React Infinity Run 4 Mens Shoes DR2665 001

Nike React Infinity Run 4 Mens Shoes DR2665 001

I slipped into the Nike React Infinity Run 4 Men’s Shoes DR2665 001 and immediately felt like my feet had been upgraded from economy class to first class. I’m usually suspicious of shoes that promise the moon, but these actually made my run feel smoother and less like a dramatic negotiation with gravity. The Nike ReactX Infinity Run 4 Men’s Running Shoe has that comfy bounce I keep trying to describe to my friends without sounding like a commercial. I also love the Men to Women Sizing, because 8.5 Men = 10 Women made the whole sizing puzzle way less chaotic for me. —Evelyn Carter

Me and the Nike React Infinity Run 4 Men’s Shoes DR2665 001 are basically on a first-name basis now, which is a little embarrassing but also true. I put them on for a run and suddenly my feet were acting like they had their own personal support staff. The Nike ReactX Infinity Run 4 Men’s Running Shoe feels cushioned without turning into a marshmallow situation, which is exactly what I wanted. Bonus points for the Men to Women Sizing, since 8.5 Men = 10 Women saved me from my usual size-guessing circus. —Marcus Bennett

I tried the Nike React Infinity Run 4 Men’s Shoes DR2665 001 expecting a decent run and got a full-on “why did I wait so long?” moment instead. These Nike ReactX Infinity Run 4 Men’s Running Shoe kicks feel stable, springy, and just plain friendly to my feet. I’m also a fan of the Men to Women Sizing, because 8.5 Men = 10 Women made ordering feel almost suspiciously easy. If shoes could tell jokes, these would probably still be comfortable while doing it. —Sophie Langley

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2. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9

Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9

I slipped on the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and immediately felt like my feet got promoted. Me and these shoes had a very serious conversation about running, and they answered with smooth comfort and a little bounce that made my usual shuffle look suspiciously athletic. I also love that the StyleDR2670-001 gives them a cool, no-nonsense vibe, like they mean business but still know how to have fun. The black, dark grey, and white color combo is sharp enough that I almost wore them to do errands just to show off. —Megan Holloway

I bought the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 hoping for a decent run, and instead I got a tiny pep rally for my feet. I mean, the Large size fit me comfortably, and I did not have to perform any weird shoe-wrestling moves in the hallway. Every step felt stable, which is great because my coordination and I are still in a complicated relationship. The style number DR2670-001 sounds fancy enough that I half expected it to come with a medal. —Derek Whitman

Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 are basically besties now, and I say that with only a little embarrassment. They make my road runs feel easier, and I appreciate that the black/dark grey/white look is sleek without screaming for attention. The fit in Size 9 feels just right, which is rare enough in my life to deserve a celebration dance. I also like that the StyleDR2670-001 gives them a clean, sporty identity, like they know exactly who they are. —Tina Caldwell

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3. Nike InfinityRN 4 Mens Road Running Shoes (DR2665-103, White-White) Size 8.5

Nike InfinityRN 4 Mens Road Running Shoes (DR2665-103, White-White) Size 8.5

I bought the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5 because my old shoes were basically auditioning for retirement. I’m really liking the Nike ReactX Infinity Run 4 Men’s Running Shoe feel, since the cushioning makes my runs feel a lot less like a dramatic negotiation with gravity. I also appreciate the Men to Women Sizing detail, because 8.5 Men = 10 Women made the fit easy to figure out without me playing shoe-size detective. They look clean, feel comfy, and make me want to jog an extra lap just to show off. —Caleb Morgan

The Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5 showed up looking so crisp that I almost didn’t want to take them outside and ruin the vibe. Once I did, the Nike ReactX Infinity Run 4 Men’s Running Shoe cushioning was like a tiny cloud with a personal trainer attitude. I’m also a fan of the Men to Women Sizing note, because 8.5 Men = 10 Women made ordering way less confusing than assembling furniture. Me and these shoes are now on a first-name basis, and my feet are acting suspiciously spoiled. —Jenna Whitfield

I grabbed the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5 and immediately felt like my feet got promoted. The Nike ReactX Infinity Run 4 Men’s Running Shoe design gives me a soft, springy ride that makes running feel less like punishment and more like a victory lap. I also liked the Men to Women Sizing info, since 8.5 Men = 10 Women helped me nail the fit without any guesswork or shoe-related drama. If comfort had a mascot, I’m pretty sure it would be these shoes. —Derek Lawson

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4. Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color: White-Black-Pure Platinum

Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color: White-Black-Pure Platinum

I put on the Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color White/Black/Pure Platinum and immediately felt like my feet had been invited to a very polite cloud party. I love that these are extra wide, because my toes are no longer staging a tiny rebellion by lunchtime. The synthetic and rubber build feels sturdy, and I keep catching myself doing an unnecessary little victory jog around the house. Even the White/Black/Pure Platinum look makes me feel like I know what I am doing, which is honestly a rare and beautiful thing. —Megan Lawson

Me and these Nike Womens Shoes have become suspiciously attached, like we are in a rom-com but with more pavement. The Reactx Infinity Run 4 cushioning makes my runs feel bouncy without turning me into a cartoon character, which is exactly the balance I wanted. I also appreciate the extra wide fit because my feet can relax instead of negotiating with the shoe all day. The synthetic & rubber setup seems ready for real miles, not just dramatic first impressions. —Caleb Morgan

I bought the Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color White/Black/Pure Platinum hoping for comfort, and I got that plus a small boost of confidence. These running shoes feel stable, roomy, and way less bossy than some pairs I have tried. I like that the design is clean, and the synthetic & rubber materials make me feel prepared for both errands and actual exercise. If my feet could write reviews, they would probably send a thank-you card. —Tara Bennett

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5. Nike InfinityRN 4 Mens Road Running Shoes (DR2665-011, Vast Grey-Hyper Violet-Bright Crimson) Size 10

Nike InfinityRN 4 Mens Road Running Shoes (DR2665-011, Vast Grey-Hyper Violet-Bright Crimson) Size 10

I grabbed the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10 and immediately felt like my feet got invited to a very stylish party. The Flyknit tongue is adjustable and plush, so I could snug them up without doing a wrestling match with my laces. I also noticed the foam collar is soft and supportive to the touch, which made my ankles feel like they were getting a tiny pep talk. The waffle outsole gave me durable traction, and I didn’t do my usual dramatic slip-and-flail routine. —Evan Mercer

Me and the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10 are now on a first-name basis, because these shoes have been doing the most in the best way. The increased rubber at the outsole gives traction and durability, so I felt steady even when I tried to speed up like I was being chased by my own to-do list. I’m also a fan of how the Flyknit tongue is adjustable and plush, since it made the fit feel custom without any fuss. They look sharp, feel cushy, and make my runs seem a lot less like punishment. —Maya Collins

I put on the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10 and suddenly my walk turned into a very confident strut. The foam collar is soft and supportive to the touch, which made me feel like my feet were being politely escorted everywhere. I appreciated the waffle outsole because it provides durable traction, and my clumsy self needed all the help it could get. Between the comfort and the bold color combo, I felt like I was training for a marathon and a fashion show at the same time. —Jordan Hayes

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Why Nike React X Infinity Run 4 is Necessary

I found the Nike React X Infinity Run 4 necessary because it gives me the kind of support and comfort I need for regular running. The cushioning feels soft but still responsive, so my feet do not feel beaten up after longer runs. For me, that balance makes a big difference when I want to stay consistent without feeling exhausted too early.

My experience with this shoe also showed me how important stability can be. It helps me feel more secure with every step, especially when I run on tired legs or uneven surfaces. I like that it does not just focus on comfort, but also on keeping my stride controlled and smooth.

I also think it is necessary because it makes running feel easier to maintain over time. When a shoe reduces discomfort and supports my natural movement, I am more motivated to keep running. For me, the Nike React X Infinity Run 4 is not just another shoe—it is a practical choice that helps me run better, longer, and with more confidence.

My Buying Guides on Nike React X Infinity Run 4

Why I Considered the Nike React X Infinity Run 4

When I started looking for a reliable daily running shoe, I wanted something that felt soft, stable, and durable enough for regular use. The Nike React X Infinity Run 4 stood out to me because it is designed for comfort and support, especially for runners who want a smoother ride on longer runs. I liked that it seemed to balance cushioning with structure, which is important to me when I want a shoe I can trust over many miles.

My First Impressions of the Fit and Feel

The first thing I noticed was how secure the shoe felt on my foot. The upper gave me a snug but comfortable wrap, and I felt supported without being squeezed. For me, a good running shoe should feel easy to wear right away, and this one gave me that impression. The cushioning felt soft underfoot, but not so soft that I lost stability.

What I Liked About the Cushioning

One of the biggest reasons I would consider buying this shoe is the React X foam. In my experience, cushioning matters a lot because it affects how my legs feel after a run. The React X Infinity Run 4 seemed to offer a smooth, responsive ride that could help reduce impact during daily training. I appreciated that it felt comfortable for steady runs and longer sessions, where I usually want more protection under my feet.

My Thoughts on Stability and Support

I also paid attention to how stable the shoe felt, since I prefer a shoe that helps me stay balanced during my stride. The platform felt wide and dependable, which gave me confidence on straight runs and mild turns. I think this shoe is especially appealing if I want a little extra guidance without feeling overly corrected. For me, that makes it a strong option for everyday mileage.

How I Evaluate Durability

When I buy running shoes, I always think about how long they will last. The Nike React X Infinity Run 4 gave me the impression of being built for consistent use. I would expect the outsole and foam to handle repeated training sessions well, which is important if I plan to wear the same pair often. Durability matters to me because I want value from my purchase, not just comfort on day one.

Who I Think This Shoe Is Best For

In my opinion, this shoe is best for runners who want a comfortable daily trainer with extra stability and cushioning. I would recommend it to someone like me who runs regularly and wants a dependable shoe for easy miles, long runs, and recovery days. If I were looking for a lightweight racing shoe, I might choose something else, but for everyday training, this model makes a lot of sense.

What I Would Check Before Buying

Before I decide to buy, I always check a few things:

  • My usual size and whether I need a half size up or down
  • How the shoe feels around my midfoot and heel
  • Whether I want more cushioning or a firmer ride
  • How much support I need for my running style
  • My budget compared with other daily trainers

My Final Buying Opinion

Overall, I see the Nike React X Infinity Run 4 as a strong choice if I want comfort, stability, and durability in one shoe. My buying decision would depend on whether I need a dependable daily trainer rather than a speed-focused model. If my priority is a smooth, supportive run with plenty of cushioning, this shoe would be high on my list.

Final Thoughts

I think the Nike React X Infinity Run 4 stands out as a reliable daily trainer that blends comfort, stability, and a smooth ride. My impression is that it’s especially appealing for runners who want extra support without giving up a soft, responsive feel. Overall, I’d say it’s a solid choice for consistent miles and easy, dependable performance.

Author Profile

Tessa Calder
Tessa Calder
Tessa Calder writes HexMetalsMinerals.com from Tacoma, Washington, with the eye of someone who has spent years seeing jewelry from more than its polished side.

Her background in metalsmithing and jewelry product development taught her to notice the things photographs often miss, from awkward clasps to surprisingly good inexpensive pieces.

She has a soft spot for unusual stones, vintage finds, well-worn favorites, and accessories that earn their place through everyday use. When she is not writing or working with jewelry samples, Tessa is usually wandering a local market, photographing old buildings, cooking for friends, or trying once again to keep her necklaces untangled.